A deadly tornado outbreak ripped through the Midwest and South over the weekend, leaving destruction, power outages and tragic loss in its wake.

Tornadoes hit the US Midwest and Southeast overnight, killing three in Missouri and causing widespread damage. Forecasters warn of a “high risk” threat for Mississippi and Alabama as storms intensify.

A monster storm system carrying a high risk tornado threat is barreling through the Southeast after unleashing deadly tornadoes, fierce winds and devastating damage across the Plains and Midwest.

Investigators with the National Weather Service will spend today working to establish the intensity of tornadoes that hit the southern U.S. Unconfirmed twisters in Alabama hit northwest of Tuscaloosa and southeast of the state capitol of Montgomery.

It’s really disturbing for what happened to the people, the casualties last night.” In Alabama, multiple tornados were confirmed, and two people were reported dead in Dallas County. An 83-year-old man,

The severe storm threat begins Saturday. Central and northern MS face heightened risk, and forecasters are warning of danger across the state.

Jeff Smitherman, the director of an Alabama emergency management agency, joins ABC News live to discuss the high-risk alert for potential tornado outbreaks in Alabama and Mississippi.