Pitcher Roki Sasaki makes his Dodgers debut as the team looks to open the season with a series sweep of the Chicago Cubs at the Tokyo Dome. First pitch is scheduled for 3:10 a.m. PDT.

The Dodgers claimed a 4-1 victory in Tuesday's opener led by Ohtani (2-for-5, two runs) and Yamamoto (5 IP, one run) and now send their newest acquisition to the mound against Cubs left-hander Justin Steele. After Wednesday's game, the teams will come back to the United States and get ready for the domestic opening day on March 27.

The MLB regular season is back and for the second straight year, the season will begin overseas in Tokyo. Last year's World Series champions, the Dodgers, will be kicking things o